Report Open Access

Strong protein sequence alignment between autoantigens involved in maternal autoantibody related autism and vaccine antigens

Arumugham, Vinu

Pandemrix vaccine induced narcolepsy was caused by molecular mimicry between the H1N1 influenza virus nucleoprotein and the human hyprocretin receptor. The BLASTP bioinformatics tool was used to determine a protein sequence alignment score between the influenza nucleoprotein and human hyprocretin receptor. This score was used as a baseline to assess autoantigen sequence alignment to vaccine antigens and contaminants. Significant protein sequence alignment was observed between autoantigens and vaccine antigens, contaminants, with numerous scores exceeding the baseline value.

Files (212.5 kB)
Name Size
MatAutTOC.pdf
md5:96afc2b8433b6d175eba8d488822c5a4
212.5 kB Download
2,636
672
views
downloads
All versions This version
Views 2,6362,637
Downloads 672672
Data volume 142.8 MB142.8 MB
Unique views 2,5872,588
Unique downloads 667667

Share

Cite as