Published June 3, 2023 | Version v1
Dataset Open

Characterization of mAMCase sugar-binding subsites

  • 1. University of California, San Francisco

Description

This directory contains all files required to characterize sugar-binding subsites across mouse AMCase structure 8FR9, 8FRA, and 8GCA as presented in Figure 2 of Díaz et al. (2023).

Structure models were analyzed in PyMOL. Figures were compiled using Adobe Illustrator.

 

Files included in this directory:

Figures

- contains PNGs of all sugar-binding subsites, canonical subsites, and noncanonical subsites with and without 2fo-fc electron density displayed.

 

PyMOL

- contains all structural models, 2mFo-DFc maps, mFo-DFc maps, PyMOL script, and PyMOL session used to generate Figure 2.

 

Contact:
Roberto Efraín Díaz, robertoefrain.diaz@ucsf.edu

James Fraser, jfraser@fraserlab.com

Files

Sugar-binding subsites.zip

Files (358.2 MB)

Name Size Download all
md5:b6c22cb84723719a3230190b8b6aa3dc
358.2 MB Preview Download

Additional details

Funding

Targeting chitin in fibrotic lung disease 5R01HL148033-03
National Institutes of Health

References

  • Díaz, Roberto Efraín et al. (2023). Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.