Published June 3, 2023 | Version v1
Dataset Open

Overview of key residues for mAMCase activity.

  • 1. University of California, San Francisco

Description

This directory contains all files to analyze the aromatic, polar, catalytic, and ligand-binding residues as well as overall protein structure as presented in Supplemental Figure 5 in the manuscript Díaz et al. (2023).

Structure models were analyzed in PyMOL. Figures were compiled using Adobe Illustrator.

 

Contact:

Roberto Efraín Díaz, robertoefrain.diaz@ucsf.edu

James Fraser, jfraser@fraserlab.com

Files

Overview.zip

Files (3.2 GB)

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md5:68165bff5087aee844482d174a92bbfd
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Additional details

Funding

Targeting chitin in fibrotic lung disease 5R01HL148033-03
National Institutes of Health

References

  • Díaz, Roberto Efraín et al. (2023). Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.